SCOPe 2.08: Domain d2cu0b1: 2cu0 B:3-95,B:207-478

Lineage for d2cu0b1 (2cu0 B:3-95,B:207-478)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)

6. Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species)

7. Species Pyrococcus horikoshii [TaxId:53953] [159379] (1 PDB entry)
   Uniprot O58045 3-96,207-480

8. Domain d2cu0b1: 2cu0 B:3-95,B:207-478 [197845]
   automated match to d2cu0a1
   complexed with xmp

Details for d2cu0b1

PDB Entry: 2cu0, 2.1 Å

PDB Description: Crystal structure of inosine-5'-monophosphate dehydrogenase from Pyrococcus horikoshii OT3

PDB Compounds: (B:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d2cu0b1:

Sequence, based on SEQRES records:

>d2cu0b1 c.1.5.1 (B:3-95,B:207-478) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]}
kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe
mavamaregglgvihrnmgieeqveqvkrvkraXkyknavrdengellvaaavspfdikr
aieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadavk
vgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaagad
avmlgnllagtkeapgkeviingrkykqyrgmgslgammkggaeryyqggymktrkfvpe
gvegvvpyrgtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphdi
iitnea

Sequence, based on observed residues (ATOM records):

>d2cu0b1 c.1.5.1 (B:3-95,B:207-478) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]}
kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe
mavamaregglgvihrnmgieeqveqvkrvkraXkyknavrdengellvaaavspfdikr
aieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadavk
vgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaagad
avmlgnllagtkeapgkeviingrkykqyrgmgslgammkymktrkfvpegvegvvpyrg
tvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphdiiitnea

Timeline for d2cu0b1:

• d2cu0b1 first appeared in SCOPe 2.03
  
• d2cu0b1 appears in SCOPe 2.07