Lineage for d4e6aa_ (4e6a A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2982128Protein MAP kinase p38 [56129] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 2982129Species Human (Homo sapiens) [TaxId:9606] [56130] (204 PDB entries)
  8. 2982289Domain d4e6aa_: 4e6a A: [197374]
    automated match to d3itza_
    complexed with 0o9

Details for d4e6aa_

PDB Entry: 4e6a (more details), 2.09 Å

PDB Description: p38a-pia23 complex
PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d4e6aa_:

Sequence, based on SEQRES records: (download)

>d4e6aa_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpp

Sequence, based on observed residues (ATOM records): (download)

>d4e6aa_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelktiwevperyqnlspvgsvcaafdtktglrvavkklsrpfqsiihakrty
relrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivqkltddhvqfli
yqilrglkyihsadiihrdlkpsnlavnedcelkildfrwyrapeimlnwmhynqtvdiw
svgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpk
mnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsf
esrdllidewksltydevisfvpp

SCOPe Domain Coordinates for d4e6aa_:

Click to download the PDB-style file with coordinates for d4e6aa_.
(The format of our PDB-style files is described here.)

Timeline for d4e6aa_: