SCOPe 2.08: Domain d3zkxa_: 3zkx A:

Lineage for d3zkxa_ (3zkx A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.0: automated matches [191552] (1 protein)
   not a true family

6. Protein automated matches [190954] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [193159] (15 PDB entries)

8. Domain d3zkxa_: 3zkx A: [197285]
   Other proteins in same PDB: d3zkxb1, d3zkxb2, d3zkxc1, d3zkxc2
   automated match to d2b8la_
   complexed with cl, dms

Details for d3zkxa_

PDB Entry: 3zkx, 2.37 Å

PDB Description: ternary bace2 xaperone complex

PDB Compounds: (A:) Beta-secretase 2

SCOPe Domain Sequences for d3zkxa_:

Sequence, based on SEQRES records:

>d3zkxa_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdtersst
yrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngil
glayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggieps
lykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfd
avveavaraslipafsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilp
qlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeia
gaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records):

>d3zkxa_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdtersst
yrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngil
glayatlakpsssletffdslvtqanipnvfsmqmcgaglggslvlggiepslykgdiwy
tpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveavar
aslipafsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilpqlyiqpml
nyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfs
tedvasncvp

Timeline for d3zkxa_:

• d3zkxa_ first appeared in SCOPe 2.02
  
• d3zkxa_ appears in SCOPe 2.07