SCOPe 2.03: Domain d3zkna_: 3zkn A:

Lineage for d3zkna_ (3zkn A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.0: automated matches [191552] (1 protein)
   not a true family

6. Protein automated matches [190954] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [193159] (11 PDB entries)

8. Domain d3zkna_: 3zkn A: [197283]
   Other proteins in same PDB: d3zknd1, d3zknd2, d3zknl1, d3zknl2
   automated match to d2qzka_
   complexed with dms, gol, so4, wzv

Details for d3zkna_

PDB Entry: 3zkn, 2 Å

PDB Description: bace2 fab inhibitor complex

PDB Compounds: (A:) Beta-secretase 2

SCOPe Domain Sequences for d3zkna_:

Sequence, based on SEQRES records:

>d3zkna_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
ilglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggie
pslykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkv
fdavveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfriti
lpqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcae
iagaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records):

>d3zkna_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
ilglayatlakpsssletffdslvtqanipnvfsmqmcganggslvlggiepslykgdiw
ytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveava
raslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilpqlyiqpm
mgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavsei
sgpfstedvasncvp

Timeline for d3zkna_:

• d3zkna_ first appeared in SCOPe 2.02
  
• d3zkna_ appears in SCOPe 2.04
  
• d3zkna_ appears in the current release, SCOPe 2.08