Lineage for d4gh8b_ (4gh8 B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2136851Protein Dihydrofolate reductase, prokaryotic type [53599] (8 species)
  7. 2136861Species Escherichia coli [TaxId:562] [53600] (78 PDB entries)
  8. 2136917Domain d4gh8b_: 4gh8 B: [197243]
    automated match to d3ql0a_
    complexed with ca, mtx, ndp

Details for d4gh8b_

PDB Entry: 4gh8 (more details), 1.85 Å

PDB Description: Crystal structure of a 'humanized' E. coli dihydrofolate reductase
PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d4gh8b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4gh8b_ c.71.1.1 (B:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}

SCOPe Domain Coordinates for d4gh8b_:

Click to download the PDB-style file with coordinates for d4gh8b_.
(The format of our PDB-style files is described here.)

Timeline for d4gh8b_: