SCOPe 2.02: Domain d3zkgb_: 3zkg B:

Lineage for d3zkgb_ (3zkg B:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.0: automated matches [191552] (1 protein)
   not a true family

6. Protein automated matches [190954] (7 species)
   not a true protein

7. Species Homo sapiens [TaxId:9606] [193159] (6 PDB entries)

8. Domain d3zkgb_: 3zkg B: [197212]
   automated match to d2b8la_
   complexed with b3p; mutant

Details for d3zkgb_

PDB Entry: 3zkg, 1.9 Å

PDB Description: bace2 mutant apo structure

PDB Compounds: (B:) Beta-secretase 2

SCOPe Domain Sequences for d3zkgb_:

Sequence, based on SEQRES records:

>d3zkgb_ b.50.1.0 (B:) automated matches {Homo sapiens [TaxId: 9606]}
lamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdtersst
yrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngil
glayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggieps
lykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfd
avveavaraslipafsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilp
qlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeia
gaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records):

>d3zkgb_ b.50.1.0 (B:) automated matches {Homo sapiens [TaxId: 9606]}
lamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdtersst
yrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngil
glayatlakpsssletffdslvtqanipnvfsmqmcganggslvlggiepslykgdiwyt
pikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveavara
ssdgfwtgsqlacwtpwsyfpkisiylrdenssrsfritilpqlyiqpmmgecyrfgisp
stnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfstedvasncvp

Timeline for d3zkgb_:

• d3zkgb_ is new in SCOPe 2.02-stable
  
• d3zkgb_ appears in SCOPe 2.03
  
• d3zkgb_ appears in the current release, SCOPe 2.08