SCOPe 2.03: Domain d4bfba_: 4bfb A:

Lineage for d4bfba_ (4bfb A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.0: automated matches [191552] (1 protein)
   not a true family

6. Protein automated matches [190954] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [193159] (11 PDB entries)

8. Domain d4bfba_: 4bfb A: [197146]
   Other proteins in same PDB: d4bfbd_, d4bfbe_
   automated match to d2qzka_
   complexed with b3p

Details for d4bfba_

PDB Entry: 4bfb, 2.21 Å

PDB Description: bace2 xaperone complex

PDB Compounds: (A:) Beta-secretase 2

SCOPe Domain Sequences for d4bfba_:

Sequence, based on SEQRES records:

>d4bfba_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
flamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdterss
tyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngi
lglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggiep
slykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvf
davveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritil
pqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaei
agaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records):

>d4bfba_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
flamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdterss
tyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngi
lglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvaggslvlggiepslykg
diwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavve
avarasldgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilpqlyiqpmmg
aglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisg
pfstedvasncvp

Timeline for d4bfba_:

• d4bfba_ first appeared in SCOPe 2.02
  
• d4bfba_ appears in SCOPe 2.04
  
• d4bfba_ appears in the current release, SCOPe 2.08