SCOPe 2.08: Domain d4gvma_: 4gvm A:

Lineage for d4gvma_ (4gvm A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (18 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)
   Pfam PF00665

6. Protein Retroviral integrase, catalytic domain [53108] (5 species)

7. Species Human immunodeficiency virus type 1 (new york-5 isolate) [TaxId:11698] [267758] (4 PDB entries)

8. Domain d4gvma_: 4gvm A: [197016]
   automated match to d1bl3c_
   complexed with ars, lf2; mutant

Details for d4gvma_

PDB Entry: 4gvm, 2.16 Å

PDB Description: hiv-1 integrase catalytic core domain a128t mutant complexed with allosteric inhibitor

PDB Compounds: (A:) Gag-Pol polyprotein

SCOPe Domain Sequences for d4gvma_:

Sequence, based on SEQRES records:

>d4gvma_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 (new york-5 isolate) [TaxId: 11698]}
dcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvktacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnkkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records):

>d4gvma_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 (new york-5 isolate) [TaxId: 11698]}
dcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvktacwwagikqefgipynpesmnkelkkiigqvrdqaehlktavqmav
fihnkkrkggggysagerivdiiatdiq

Timeline for d4gvma_:

• d4gvma_ first appeared in SCOPe 2.02
  
• d4gvma_ appears in SCOPe 2.07