SCOPe 2.08: Domain d4iz7c_: 4iz7 C:

Lineage for d4iz7c_ (4iz7 C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase Erk2 [56134] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56135] (74 PDB entries)

8. Domain d4iz7c_: 4iz7 C: [196907]
   automated match to d3sa0a_
   complexed with na

Details for d4iz7c_

PDB Entry: 4iz7, 1.8 Å

PDB Description: Structure of Non-Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain

PDB Compounds: (C:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d4iz7c_:

Sequence, based on SEQRES records:

>d4iz7c_ d.144.1.7 (C:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
pemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvat
rwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqe
dlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalah
pyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyr

Sequence, based on observed residues (ATOM records):

>d4iz7c_ d.144.1.7 (C:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
pemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpeyvatrwyrapeim
lnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlk
arnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydp
sdepiaeapfkfdmelddlpkeklkelifeetarfqpgyr

Timeline for d4iz7c_:

• d4iz7c_ first appeared in SCOPe 2.02
  
• d4iz7c_ appears in SCOPe 2.07