SCOPe 2.03: Domain d4eiza_: 4eiz A:

Lineage for d4eiza_ (4eiz A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductase, prokaryotic type [53599] (8 species)

7. Species Escherichia coli [TaxId:562] [53600] (61 PDB entries)

8. Domain d4eiza_: 4eiz A: [196881]
   Other proteins in same PDB: d4eizc_, d4eizd_
   automated match to d3daua_

Details for d4eiza_

PDB Entry: 4eiz, 2.2 Å

PDB Description: Structure of Nb113 bound to apoDHFR

PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d4eiza_:

Sequence; same for both SEQRES and ATOM records:

>d4eiza_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

Timeline for d4eiza_:

• d4eiza_ first appeared in SCOPe 2.02
  
• d4eiza_ appears in SCOPe 2.04
  
• d4eiza_ appears in the current release, SCOPe 2.08