SCOPe 2.06: Domain d3zh8b_: 3zh8 B:

Lineage for d3zh8b_ (3zh8 B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d3zh8b_: 3zh8 B: [196875]
   automated match to d3a8xa_
   complexed with c58, cl, edo, iod

Details for d3zh8b_

PDB Entry: 3zh8, 2.74 Å

PDB Description: a novel small molecule apkc inhibitor

PDB Compounds: (B:) Protein kinase C iota type

SCOPe Domain Sequences for d3zh8b_:

Sequence, based on SEQRES records:

>d3zh8b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slglqdfdllrvigrgsyakvllvrlkktdriyamkvvkkelvnddedidwvqtekhvfe
qasnhpflvglhscfqtesrlffvieyvnggdlmfhmqrqrklpeeharfysaeislaln
ylhergiiyrdlkldnvlldseghikltdygmckeglrpgdttstfcgtpnyiapeilrg
edygfsvdwwalgvlmfemmagrspfdivgssdnpdqntedylfqvilekqiriprslsv
kaasvlksflnkdpkerlgchpqtgfadiqghpffrnvdwdmmeqkqvvppfkpnisgef
gldnfdsqftnepvqltpddddivrkidqsefegfeyinpll

Sequence, based on observed residues (ATOM records):

>d3zh8b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slglqdfdllrvigrgsyakvllvrlkktdriyamkvvkkelvnddedidwvqtekhvfe
qasnhpflvglhscfqtesrlffvieyvnggdlmfhmqrqrklpeeharfysaeislaln
ylhergiiyrdlkldnvlldseghikltdygmckeglrpgdttstfcgtpnyiapeilrg
edygfsvdwwalgvlmfemmagrspfdivntedylfqvilekqiriprslsvkaasvlks
flnkdpkerlgchpqtgfadiqghpffrnvdwdmmeqkqvvppfkpnisgeqltpddddi
vrkidqsefegfeyinpll

Timeline for d3zh8b_:

• d3zh8b_ first appeared in SCOPe 2.02
  
• d3zh8b_ appears in SCOPe 2.05
  
• d3zh8b_ appears in SCOPe 2.07
  
• d3zh8b_ appears in the current release, SCOPe 2.08