Lineage for d4jika_ (4jik A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1221476Protein automated matches [190091] (10 species)
    not a true protein
  7. 1221597Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)
  8. 1221698Domain d4jika_: 4jik A: [196866]
    automated match to d2x8da_
    complexed with 1ko

Details for d4jika_

PDB Entry: 4jik (more details), 1.9 Å

PDB Description: X-RAY Crystal structure of compound 22a (R)-2-(4-chlorophenyl)-8-(piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide bound to human chk1 kinase domain
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d4jika_:

Sequence, based on SEQRES records: (download)

>d4jika_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmln
henvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhg
igithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrre
fhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallh
kilvenpsaritipdikkdrwynkplkkg

Sequence, based on observed residues (ATOM records): (download)

>d4jika_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pfvedwdlvqtlgegagevqlavnrvteeavavkivnikkeicinkmlnhenvvkfyghr
reiqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenl
llderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgi
vltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsariti
pdikkdrwynkplkkg

SCOPe Domain Coordinates for d4jika_:

Click to download the PDB-style file with coordinates for d4jika_.
(The format of our PDB-style files is described here.)

Timeline for d4jika_: