Lineage for d4hvsa_ (4hvs A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674179Domain d4hvsa_: 4hvs A: [196842]
    automated match to d1t45a_
    complexed with 647

Details for d4hvsa_

PDB Entry: 4hvs (more details), 1.9 Å

PDB Description: Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX647
PDB Compounds: (A:) Mast/stem cell growth factor receptor Kit

SCOPe Domain Sequences for d4hvsa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4hvsa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hhmpmyevqwkvveesngnnysyidptqlpydhkwefprnrlsfgktlgagafgkvveat
aqgliksdaamtvavkmlkpsahsterealmselkvlsylgnhenivnllgacthggptl
viteyccygdllnflrrkrdsfhssdtspasmeddenaldledllsfsyqvakgmaflas
kncihrdlaarnillthgritkicdfglardikndsnyvdkgnarlpvkwmapesifnsv
ytfesdvwsygiflwelfslgsspypgmpvdskfykmikegfrmsspehapaemydimkt
cwdadpdkrptfkqivqdiekqises

SCOPe Domain Coordinates for d4hvsa_:

Click to download the PDB-style file with coordinates for d4hvsa_.
(The format of our PDB-style files is described here.)

Timeline for d4hvsa_: