SCOPe 2.05: Domain d4f6za_: 4f6z A:

Lineage for d4f6za_ (4f6z A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
   duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

4. Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (15 families)

5. Family d.157.1.1: Zn metallo-beta-lactamase [56282] (2 proteins)

6. Protein Zn metallo-beta-lactamase [56283] (12 species)

7. Species Pseudomonas aeruginosa, IMP-1 [TaxId:287] [56287] (7 PDB entries)

8. Domain d4f6za_: 4f6z A: [196711]
   automated match to d1jjeb_
   complexed with flc, zn

Details for d4f6za_

PDB Entry: 4f6z, 2 Å

PDB Description: mutagenesis of zinc ligand residue cys221 reveals plasticity in the imp-1 metallo-b-lactamase active site

PDB Compounds: (A:) Beta-lactamase

SCOPe Domain Sequences for d4f6za_:

Sequence, based on SEQRES records:

>d4f6za_ d.157.1.1 (A:) Zn metallo-beta-lactamase {Pseudomonas aeruginosa, IMP-1 [TaxId: 287]}
pdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtwfv
ergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvnyw
lvknkievfypgpghtpdnvvvwlperkilfgggfikpyglgnlgdanieawpksakllk
skygkaklvvpshsevgdasllkltleqavkglneskkpskpsnwshpqfek

Sequence, based on observed residues (ATOM records):

>d4f6za_ d.157.1.1 (A:) Zn metallo-beta-lactamase {Pseudomonas aeruginosa, IMP-1 [TaxId: 287]}
pdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtwfv
ergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvnyw
lvknkievfypgpghtpdnvvvwlperkilfgggfikpyglgnlgdanieawpksakllk
skygkaklvvpshsevgdasllkltleqavkglnehpqfek

Timeline for d4f6za_:

• d4f6za_ first appeared in SCOPe 2.02
  
• d4f6za_ appears in SCOPe 2.04
  
• d4f6za_ is called d4f6za1 in SCOPe 2.06
  
• d4f6za_ appears in the current release, SCOPe 2.08, called d4f6za1