Lineage for d4au8b_ (4au8 B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2545120Protein automated matches [190091] (20 species)
    not a true protein
  7. 2545220Species Human (Homo sapiens) [TaxId:9606] [188447] (770 PDB entries)
  8. 2545341Domain d4au8b_: 4au8 B: [196697]
    Other proteins in same PDB: d4au8a2
    automated match to d1unla_
    complexed with imd, so4, z3r

Details for d4au8b_

PDB Entry: 4au8 (more details), 1.9 Å

PDB Description: Crystal structure of compound 4a in complex with cdk5, showing an unusual binding mode to the hinge region via a water molecule
PDB Compounds: (B:) cyclin-dependent kinase 5

SCOPe Domain Sequences for d4au8b_:

Sequence, based on SEQRES records: (download)

>d4au8b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qkyeklekigegtygtvfkaknretheivalkrvrlddddegvpssalreicllkelkhk
nivrlhdvlhsdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsrn
vlhrdlkpqnllinrngelkladfglarafgipvrcysaevvtlwyrppdvlfgaklyst
sidmwsagcifaelanagrplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpypm
ypattslvnvvpklnatgrdllqnllkcnpvqrisaeealqhpyfsdf

Sequence, based on observed residues (ATOM records): (download)

>d4au8b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qkyeklekigegtygtvfkaknretheivalkrvrlegvpssalreicllkelkhknivr
lhdvlhskkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsrnvlhrd
lkpqnllinrngelkladfglarafgipvvvtlwyrppdvlfgaklystsidmwsagcif
aelanagrplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpypmypattslvnvv
pklnatgrdllqnllkcnpvqrisaeealqhpyfsdf

SCOPe Domain Coordinates for d4au8b_:

Click to download the PDB-style file with coordinates for d4au8b_.
(The format of our PDB-style files is described here.)

Timeline for d4au8b_: