SCOPe 2.02: Domain d3et3a_: 3et3 A:

Lineage for d3et3a_ (3et3 A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (12 species)
   not a true protein

7. Species Homo sapiens [TaxId:9606] [192490] (10 PDB entries)

8. Domain d3et3a_: 3et3 A: [196608]
   automated match to d3cs8a_
   complexed with et1

Details for d3et3a_

PDB Entry: 3et3, 1.95 Å

PDB Description: Structure of PPARgamma with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3et3a_:

Sequence, based on SEQRES records:

>d3et3a_ a.123.1.1 (A:) automated matches {Homo sapiens [TaxId: 9606]}
mesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfk
hitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhei
iytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdla
ifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqi
vtehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d3et3a_ a.123.1.1 (A:) automated matches {Homo sapiens [TaxId: 9606]}
mesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdmslhpllqeiykdly

Timeline for d3et3a_:

• d3et3a_ is new in SCOPe 2.02-stable
  
• d3et3a_ appears in SCOPe 2.03
  
• d3et3a_ appears in the current release, SCOPe 2.08, called d3et3a1