SCOPe 2.03: Domain d3k1oa_: 3k1o A:

Lineage for d3k1oa_ (3k1o A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (33 species)
   not a true protein

7. Species Trypanosoma cruzi [TaxId:5693] [196511] (3 PDB entries)

8. Domain d3k1oa_: 3k1o A: [196522]
   automated match to d3l4da_
   complexed with hem, poz

Details for d3k1oa_

PDB Entry: 3k1o, 2.89 Å

PDB Description: crystal structure of sterol 14-alpha demethylase (cyp51) from trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole

PDB Compounds: (A:) Sterol 14 alpha-demethylase

SCOPe Domain Sequences for d3k1oa_:

Sequence, based on SEQRES records:

>d3k1oa_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ktppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrf
fsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhe
vrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessli
paavfmpwllrlplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggllkav
yrdgtrmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaq
lnydnvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshh
deeafpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllr
devpdpdyhtmvvgptlnqclvkytrkk

Sequence, based on observed residues (ATOM records):

>d3k1oa_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ktppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrf
fsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhe
vrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessli
paavfmplplpqsarcrearaelqkilgeiivarekeeaskntsdllggllkavyrdgtr
mslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqlnydnv
mdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhdeeafp
nprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrdevpdp
dyhtmvvgptlnqclvkytrkk

Timeline for d3k1oa_:

• d3k1oa_ first appeared in SCOPe 2.02
  
• d3k1oa_ appears in SCOPe 2.04
  
• d3k1oa_ appears in the current release, SCOPe 2.08