SCOPe 2.02: Domain d3iw4c_: 3iw4 C:

Lineage for d3iw4c_ (3iw4 C:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Homo sapiens [TaxId:9606] [192729] (55 PDB entries)

8. Domain d3iw4c_: 3iw4 C: [196517]
   automated match to d2i0ea_
   complexed with lw4

Details for d3iw4c_

PDB Entry: 3iw4, 2.8 Å

PDB Description: crystal structure of pkc alpha in complex with nvp-aeb071

PDB Compounds: (C:) Protein kinase C alpha type

SCOPe Domain Sequences for d3iw4c_:

Sequence, based on SEQRES records:

>d3iw4c_ d.144.1.7 (C:) automated matches {Homo sapiens [TaxId: 9606]}
nldrvkltdfnflmvlgkgsfgkvmladrkgteelyaikilkkdvviqdddvectmvekr
vlalldkppfltqlhscfqtvdrlyfvmeyvnggdlmyhiqqvgkfkepqavfyaaeisi
glfflhkrgiiyrdlkldnvmldseghikiadfgmckehmmdgvttrefcgtpdyiapei
iayqpygksvdwwaygvllyemlagqppfdgededelfqsimehnvsypkslskeavsic
kglmtkhpakrlgcgpegerdvrehaffrridweklenreiqppfkpkvcgkgaenfdkf
ftrgqpvltppdqlvianidqsdfegfsyvnpqfvhpilqs

Sequence, based on observed residues (ATOM records):

>d3iw4c_ d.144.1.7 (C:) automated matches {Homo sapiens [TaxId: 9606]}
nldrvkltdfnflmvlgkgsfgkvmladrkgteelyaikilkkdvviqdddvectmvekr
vlalldkppfltqlhscfqtvdrlyfvmeyvnggdlmyhiqqvgkfkepqavfyaaeisi
glfflhkrgiiyrdlkldnvmldseghikiadfgmckehmmdgvttrefcgtpdyiapei
iayqpygksvdwwaygvllyemlagqppfdgededelfqsimehnvsypkslskeavsic
kglmtkhpakrlgcgpegerdvrehaffrridweklenreiqppfkpkvfdkfftrgqpv
ltppdqlvianidqsdfegfsyvnpqfvhpilqs

Timeline for d3iw4c_:

• d3iw4c_ is new in SCOPe 2.02-stable
  
• d3iw4c_ appears in SCOPe 2.03
  
• d3iw4c_ appears in the current release, SCOPe 2.08