Lineage for d3k54a_ (3k54 A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220941Protein automated matches [190091] (17 species)
    not a true protein
  7. 2221040Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2221213Domain d3k54a_: 3k54 A: [196486]
    automated match to d3pj2a_
    complexed with 1n1

Details for d3k54a_

PDB Entry: 3k54 (more details), 1.94 Å

PDB Description: Structures of human Bruton's tyrosine kinase in active and inactive conformations suggests a mechanism of activation for TEC family kinases.
PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d3k54a_:

Sequence, based on SEQRES records: (download)

>d3k54a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmn
lsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceamey
leskqflhrdlaarnclvndqgvvkvsdfglsryvlddeetssvgskfpvrwsppevlmy
skfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimy
scwhekaderptfkillsnildvmdee

Sequence, based on observed residues (ATOM records): (download)

>d3k54a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikefieeakvmmnlsheklv
qlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyleskqfl
hrdlaarnclvndqgvvkvsdfgfpvrwsppevlmyskfssksdiwafgvlmweiyslgk
mpyerftnsetaehiaqglrlyrphlasekvytimyscwhekaderptfkillsnildvm
dee

SCOPe Domain Coordinates for d3k54a_:

Click to download the PDB-style file with coordinates for d3k54a_.
(The format of our PDB-style files is described here.)

Timeline for d3k54a_: