SCOPe 2.02: Domain d3laua_: 3lau A:

Lineage for d3laua_ (3lau A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)

8. Domain d3laua_: 3lau A: [196469]
   automated match to d3fdna_
   complexed with ofi

Details for d3laua_

PDB Entry: 3lau, 2.1 Å

PDB Description: crystal structure of aurora2 kinase in complex with a gsk3beta inhibitor

PDB Compounds: (A:) serine/threonine-protein kinase 6

SCOPe Domain Sequences for d3laua_:

Sequence, based on SEQRES records:

>d3laua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreve
iqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelana
lsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrtdlcgtldylppemieg
rmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrl
lkhnpsqrpmlrevlehpwitansskps

Sequence, based on observed residues (ATOM records):

>d3laua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreve
iqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelana
lsychskrvihrdikpenlllgsagelkiadfldylppemiegrmhdekvdlwslgvlcy
eflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrevleh
pwitansskps

Timeline for d3laua_:

• d3laua_ is new in SCOPe 2.02-stable
  
• d3laua_ appears in SCOPe 2.03
  
• d3laua_ appears in the current release, SCOPe 2.08, called d3laua1