Lineage for d3u6ja_ (3u6j A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674241Domain d3u6ja_: 3u6j A: [195995]
    automated match to d2p2ha_
    complexed with 03x

Details for d3u6ja_

PDB Entry: 3u6j (more details), 2.15 Å

PDB Description: Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor
PDB Compounds: (A:) Vascular endothelial growth factor receptor 2

SCOPe Domain Sequences for d3u6ja_:

Sequence, based on SEQRES records: (download)

>d3u6ja_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ehcerlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlkega
thsehralmselkilihighhlnvvnllgactkpggplmvitefckfgnlstylrskrne
fvpykvapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvki
cdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgas
pypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnll
qanaqqdrhh

Sequence, based on observed residues (ATOM records): (download)

>d3u6ja_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ehcerlpydaskwefprdrlklgkplgrgafgqvieadafgidatcrtvavkmlkegath
sehralmselkilihighhlnvvnllgactkpggplmvitefckfgnlstylrskrnefv
pykvapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicd
fglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgaspy
pgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllqa
naqqdrhh

SCOPe Domain Coordinates for d3u6ja_:

Click to download the PDB-style file with coordinates for d3u6ja_.
(The format of our PDB-style files is described here.)

Timeline for d3u6ja_: