Lineage for d3s54a_ (3s54 A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2058816Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2058832Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2059066Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (466 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 2059203Domain d3s54a_: 3s54 A: [195773]
    automated match to d2hs1a_
    complexed with 017, act, cl, gol, na; mutant

Details for d3s54a_

PDB Entry: 3s54 (more details), 1.42 Å

PDB Description: HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212
PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d3s54a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3s54a_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}

SCOPe Domain Coordinates for d3s54a_:

Click to download the PDB-style file with coordinates for d3s54a_.
(The format of our PDB-style files is described here.)

Timeline for d3s54a_: