Lineage for d3s45a_ (3s45 A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2058816Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2058832Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2058989Species Human immunodeficiency virus 2 [TaxId:11709] [195770] (1 PDB entry)
  8. 2058990Domain d3s45a_: 3s45 A: [195771]
    automated match to d1hsha_
    complexed with 478, cl, imd, na, zn

Details for d3s45a_

PDB Entry: 3s45 (more details), 1.51 Å

PDB Description: wild-type HIV-2 protease with antiviral drug amprenavir
PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d3s45a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3s45a_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus 2 [TaxId: 11709]}

SCOPe Domain Coordinates for d3s45a_:

Click to download the PDB-style file with coordinates for d3s45a_.
(The format of our PDB-style files is described here.)

Timeline for d3s45a_: