SCOPe 2.05: Domain d3v6mj_: 3v6m J:

Lineage for d3v6mj_ (3v6m J:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.0: automated matches [191651] (1 protein)
   not a true family

6. Protein automated matches [191201] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189525] (14 PDB entries)

8. Domain d3v6mj_: 3v6m J: [195682]
   automated match to d3od5a_
   mutant

Details for d3v6mj_

PDB Entry: 3v6m, 2.69 Å

PDB Description: Inhibition of caspase-6 activity by single mutation outside the active site

PDB Compounds: (J:) Caspase-6

SCOPe Domain Sequences for d3v6mj_:

Sequence, based on SEQRES records:

>d3v6mj_ c.17.1.0 (J:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fdpaekykmdhrrrgialifnherffwhltlperrgtcadrdnltrrfsdlgfevkcfnd
lkaeelllkihevstvshadadcfvcvflshgegnhiyaydakieiqtltglfkgdkchs
lvgkpkifiiqacrgnqhdvpvipldvvdnqtekldtnitevdaasvytlpagadflmcy
svaegyyshretvngswyiqdlcemlgkygssleftelltlvnrkveqrrvdfckdpsai
gkkqvpcfasmltkklhffpks

Sequence, based on observed residues (ATOM records):

>d3v6mj_ c.17.1.0 (J:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fdpaekykmdhrrrgialifnherffwhltlperrgtcadrdnltrrfsdlgfevkcfnd
lkaeelllkihevstvshadadcfvcvflshgegnhiyaydakieiqtltglfkgdkchs
lvgkpkifiiqacytlpagadflmcysvtvngswyiqdlcemlgkygssleftelltlvn
rkveqrrvvpcfasmltkklhffpks

Timeline for d3v6mj_:

• d3v6mj_ first appeared in SCOPe 2.02
  
• d3v6mj_ appears in SCOPe 2.04
  
• d3v6mj_ appears in SCOPe 2.06
  
• d3v6mj_ appears in the current release, SCOPe 2.08