Lineage for d3td8a_ (3td8 A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2510888Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2510889Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2510890Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2511215Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2511237Species Fungus (Pneumocystis carinii) [TaxId:4754] [53608] (25 PDB entries)
  8. 2511246Domain d3td8a_: 3td8 A: [195600]
    automated match to d3nzbx_
    complexed with d2r, ndp

Details for d3td8a_

PDB Entry: 3td8 (more details), 1.8 Å

PDB Description: Structural Analysis of Pneumocystis carinii Dihydrofolate Reductase Complex with NADPH and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d3td8a_:

Sequence, based on SEQRES records: (download)

>d3td8a_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Fungus (Pneumocystis carinii) [TaxId: 4754]}
ksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrktwes
iplqfrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinrifvig
gaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdleswvgtk
vphgkinedgfdyefemwtrdl

Sequence, based on observed residues (ATOM records): (download)

>d3td8a_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Fungus (Pneumocystis carinii) [TaxId: 4754]}
ksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrktwes
iplqfrplkgrinvvitrnihsaksldhalellyrtygsessvqinrifviggaqlykaa
mdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdleswvgtkvphgkine
dgfdyefemwtrdl

SCOPe Domain Coordinates for d3td8a_:

Click to download the PDB-style file with coordinates for d3td8a_.
(The format of our PDB-style files is described here.)

Timeline for d3td8a_: