SCOPe 2.07: Domain d2z2wa_: 2z2w A:

Lineage for d2z2wa_ (2z2w A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d2z2wa_: 2z2w A: [195304]
   automated match to d2a19b_
   complexed with 770, cl, gol

Details for d2z2wa_

PDB Entry: 2z2w, 2.22 Å

PDB Description: human wee1 kinase complexed with inhibitor pf0335770

PDB Compounds: (A:) Wee1-like protein kinase

SCOPe Domain Sequences for d2z2wa_:

Sequence, based on SEQRES records:

>d2z2wa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mksryttefhelekigsgefgsvfkcvkrldgciyaikrskkplagsvdeqnalrevyah
avlgqhshvvryfsawaeddhmliqneycnggsladaisenyrimsyfkeaelkdlllqv
grglryihsmslvhmdikpsnifisrtsipnaaseegdeddwasnkvmfkigdlghvtri
sspqveegdsrflanevlqenythlpkadifalaltvvcaagaeplprngdqwheirqgr
lpripqvlsqeftellkvmihpdperrpsamalvkhsvlls

Sequence, based on observed residues (ATOM records):

>d2z2wa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mksryttefhelekigsgefgsvfkcvkrldgciyaikrskkplagsvdeqnalrevyah
avlgqhshvvryfsawaeddhmliqneycnggsladaisenyrimsyfkeaelkdlllqv
grglryihsmslvhmdikpsnifiskvmfkigdlghvtrisspqveegdsrflanevlqe
nythlpkadifalaltvvcaagaeplprngdqwheirqgrlpripqvlsqeftellkvmi
hpdperrpsamalvkhsvlls

Timeline for d2z2wa_:

• d2z2wa_ first appeared in SCOPe 2.02
  
• d2z2wa_ appears in SCOPe 2.06
  
• d2z2wa_ appears in the current release, SCOPe 2.08