Lineage for d2o8ua_ (2o8u A:)

  1. Root: SCOPe 2.02
  2. 1103260Class b: All beta proteins [48724] (174 folds)
  3. 1127558Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 1127559Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 1127765Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)
  6. 1129221Protein automated matches [190044] (13 species)
    not a true protein
  7. 1129253Species Human (Homo sapiens) [TaxId:9606] [187233] (122 PDB entries)
  8. 1129288Domain d2o8ua_: 2o8u A: [194811]
    automated match to d2viva_
    complexed with ben, peg, pg4, so4

Details for d2o8ua_

PDB Entry: 2o8u (more details), 1.7 Å

PDB Description: crystal structure and binding epitopes of urokinase-type plasminogen activator (c122a/n145q/s195a) in complex with inhibitors
PDB Compounds: (A:) Urokinase plasminogen activator

SCOPe Domain Sequences for d2o8ua_:

Sequence, based on SEQRES records: (download)

>d2o8ua_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdaggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irsht

Sequence, based on observed residues (ATOM records): (download)

>d2o8ua_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iiggefttienqpwfaaiyrrvtyvcggslispcwvisathcfidypkkedyivylgrsr
lnsntqgemkfevenlilhkdysadahhndiallkirskegrcaqpsrtiqtialpsmyn
dpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttkmlcaadp
qwktdscqgdaggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpwirsht

SCOPe Domain Coordinates for d2o8ua_:

Click to download the PDB-style file with coordinates for d2o8ua_.
(The format of our PDB-style files is described here.)

Timeline for d2o8ua_: