SCOPe 2.02: Domain d4fsua_: 4fsu A:

Lineage for d4fsua_ (4fsu A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)

8. Domain d4fsua_: 4fsu A: [194786]
   automated match to d2x8da_
   complexed with gol, hk5, ipa, so4

Details for d4fsua_

PDB Entry: 4fsu, 2.1 Å

PDB Description: Crystal Structure of the CHK1

PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d4fsua_:

Sequence, based on SEQRES records:

>d4fsua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pfvedwdlvqtlgegaagevqlavnrvteeavavkivdmkravdcpenikkeicinkmln
henvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhg
igithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrre
fhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallh
kilvenpsaritipdikkdrwynkplkk

Sequence, based on observed residues (ATOM records):

>d4fsua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pfvedwdlvqtlgegaagevqlavnrvteeavavkivdenikkeicinkmlnhenvvkfy
ghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdi
kpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdv
wscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenps
aritipdikkdrwynkplkk

Timeline for d4fsua_:

• d4fsua_ is new in SCOPe 2.02-stable
  
• d4fsua_ appears in SCOPe 2.03
  
• d4fsua_ appears in the current release, SCOPe 2.08