SCOPe 2.07: Domain d3uucb_: 3uuc B:

Lineage for d3uucb_ (3uuc B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d3uucb_: 3uuc B: [194775]
   automated match to d3q95b_
   complexed with 0d1

Details for d3uucb_

PDB Entry: 3uuc, 2.1 Å

PDB Description: Crystal structure of hERa-LBD (wt) in complex with bisphenol-C

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d3uucb_:

Sequence, based on SEQRES records:

>d3uucb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemld
ahrlhap

Sequence, based on observed residues (ATOM records):

>d3uucb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgegmveifdml
latssrfrmmnlqgeefvclksiillnsgvleekdhihrvldkitdtlihlmakagltlq
qqhqrlaqlllilshirhmsnkgmehlysmvvplydlllemldahrlhap

Timeline for d3uucb_:

• d3uucb_ first appeared in SCOPe 2.02
  
• d3uucb_ appears in SCOPe 2.06
  
• d3uucb_ appears in the current release, SCOPe 2.08