SCOPe 2.08: Domain d3uuca_: 3uuc A:

Lineage for d3uuca_ (3uuc A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d3uuca_: 3uuc A: [194773]
   automated match to d3q95b_
   complexed with 0d1

Details for d3uuca_

PDB Entry: 3uuc, 2.1 Å

PDB Description: Crystal structure of hERa-LBD (wt) in complex with bisphenol-C

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d3uuca_:

Sequence, based on SEQRES records:

>d3uuca_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml

Sequence, based on observed residues (ATOM records):

>d3uuca_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptreasmmglltnladrelvhminwakrvpgf
vdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytfsleekdhihrvldkitdtlihlmakaglt
lqqqhqrlaqlllilshirhmsnkgmehlysmkydllleml

Timeline for d3uuca_:

• d3uuca_ first appeared in SCOPe 2.02
  
• d3uuca_ appears in SCOPe 2.07