Lineage for d4g5ja_ (4g5j A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1221476Protein automated matches [190091] (10 species)
    not a true protein
  7. 1221539Species Homo sapiens [TaxId:9606] [192729] (55 PDB entries)
  8. 1221585Domain d4g5ja_: 4g5j A: [194750]
    automated match to d2gs6a_
    complexed with 0wm, 0wn

Details for d4g5ja_

PDB Entry: 4g5j (more details), 2.8 Å

PDB Description: Crystal structure of EGFR kinase in complex with BIBW2992
PDB Compounds: (A:) Epidermal growth factor receptor

SCOPe Domain Sequences for d4g5ja_:

Sequence, based on SEQRES records: (download)

>d4g5ja_ d.144.1.7 (A:) automated matches {Homo sapiens [TaxId: 9606]}
geapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspka
nkeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyll
nwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggk
vpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpq
ppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptds
nfyralmdeedmddvvdadey

Sequence, based on observed residues (ATOM records): (download)

>d4g5ja_ d.144.1.7 (A:) automated matches {Homo sapiens [TaxId: 9606]}
geapnqallrilketefkkikvlgstvykglwipegekvkipvaikekeildeayvmasv
dnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqiakgmnyle
drrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpikwmalesilhr
iythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimvk
cwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyralmdeedmdd
vvdadey

SCOPe Domain Coordinates for d4g5ja_:

Click to download the PDB-style file with coordinates for d4g5ja_.
(The format of our PDB-style files is described here.)

Timeline for d4g5ja_: