SCOPe 2.05: Domain d4gsba_: 4gsb A:

Lineage for d4gsba_ (4gsb A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase Erk2 [56134] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [56136] (27 PDB entries)

8. Domain d4gsba_: 4gsb A: [194705]
   automated match to d1erka_
   complexed with gol, pge, so4

Details for d4gsba_

PDB Entry: 4gsb, 1.8 Å

PDB Description: Monoclinic crystal form of the apo-ERK2

PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d4gsba_:

Sequence, based on SEQRES records:

>d4gsba_ d.144.1.7 (A:) MAP kinase Erk2 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
pemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqrtlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvat
rwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqe
dlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalah
pyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy

Sequence, based on observed residues (ATOM records):

>d4gsba_ d.144.1.7 (A:) MAP kinase Erk2 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
pemvrgqvfdvgprytnlsyigegmvcsaydnlnkvrvaikkispfehqtycqrtlreik
illrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyflyqi
lrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrwy
rapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedln
ciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyl
eqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy

Timeline for d4gsba_:

• d4gsba_ first appeared in SCOPe 2.02
  
• d4gsba_ appears in SCOPe 2.04
  
• d4gsba_ appears in SCOPe 2.06
  
• d4gsba_ appears in the current release, SCOPe 2.08