Lineage for d4fqfc_ (4fqf C:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2515970Fold c.82: ALDH-like [53719] (1 superfamily)
    consists of two similar domains with 3 layers (a/b/a) each; duplication
    core: parallel beta-sheet of 5 strands, order 32145
  4. 2515971Superfamily c.82.1: ALDH-like [53720] (3 families) (S)
    binds NAD differently from other NAD(P)-dependent oxidoreductases
  5. 2515972Family c.82.1.1: ALDH-like [53721] (6 proteins)
  6. 2515977Protein Aldehyde reductase (dehydrogenase), ALDH [53722] (9 species)
  7. 2516001Species Human (Homo sapiens), mitochondrial [TaxId:9606] [53726] (27 PDB entries)
    Uniprot P05091
  8. 2516044Domain d4fqfc_: 4fqf C: [194632]
    automated match to d1bi9a_
    complexed with 2no, mg, na, nad, ure

Details for d4fqfc_

PDB Entry: 4fqf (more details), 2.28 Å

PDB Description: Crystal structure of a thionitrate intermediate of human aldehyde dehydrogenase-2
PDB Compounds: (C:) aldehyde dehydrogenase, mitochondrial

SCOPe Domain Sequences for d4fqfc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4fqfc_ c.82.1.1 (C:) Aldehyde reductase (dehydrogenase), ALDH {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
vpapnqqpevfcnqifinnewhdavsrktfptvnpstgevicqvaegdkedvdkavkaar
aafqlgspwrrmdashrgrllnrladlierdrtylaaletldngkpyvisylvdldmvlk
clryyagwadkyhgktipidgdffsytrhepvgvcgqiipwnfpllmqawklgpalatgn
vvvmkvaeqtpltalyvanlikeagfppgvvnivpgfgptagaaiashedvdkvaftgst
eigrviqvaagssnlkrvtlelggkspniimsdadmdwaveqahfalffnqgqcccagsr
tfvqediydefversvaraksrvvgnpfdskteqgpqvdetqfkkilgyintgkqegakl
lcgggiaadrgyfiqptvfgdvqdgmtiakeeifgpvmqilkfktieevvgrannstygl
aaavftkdldkanylsqalqagtvwvncydvfgaqspfggykmsgsgrelgeyglqayte
vktvtvkvpqkns

SCOPe Domain Coordinates for d4fqfc_:

Click to download the PDB-style file with coordinates for d4fqfc_.
(The format of our PDB-style files is described here.)

Timeline for d4fqfc_: