Lineage for d2v7ab_ (2v7a B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2545120Protein automated matches [190091] (19 species)
    not a true protein
  7. 2545220Species Human (Homo sapiens) [TaxId:9606] [188447] (741 PDB entries)
  8. 2545931Domain d2v7ab_: 2v7a B: [194610]
    automated match to d3ik3a_
    complexed with 627, mg; mutant

Details for d2v7ab_

PDB Entry: 2v7a (more details), 2.5 Å

PDB Description: crystal structure of the t315i abl mutant in complex with the inhibitor pha-739358
PDB Compounds: (B:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2v7ab_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2v7ab_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmkei
khpnlvqllgvctreppfyiiiefmtygnlldylrecnrqevnavvllymatqissamey
lekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslay
nkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmr
acwqwnpsdrpsfaeihqafetmfqessis

SCOPe Domain Coordinates for d2v7ab_:

Click to download the PDB-style file with coordinates for d2v7ab_.
(The format of our PDB-style files is described here.)

Timeline for d2v7ab_: