SCOPe 2.08: Domain d4e1za_: 4e1z A:

Lineage for d4e1za_ (4e1z A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [194605] (31 PDB entries)

8. Domain d4e1za_: 4e1z A: [194607]
   automated match to d3nz0a_
   complexed with 0mx

Details for d4e1za_

PDB Entry: 4e1z, 2.5 Å

PDB Description: Structure of mouse Tyk-2 complexed to a 3-aminoindazole inhibitor

PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d4e1za_:

Sequence, based on SEQRES records:

>d4e1za_ d.144.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
sdptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkegcgpqlrsgwqr
eieilrtlyhehivkykgccedqgeksvqlvmeyvplgslrdylprhcvglaqlllfaqq
icegmaylhaqhyihralaarnvlldndrlvkigdfglakavpegheyyrvredgdspvf
wyapeclkeckfyyasdvwsfgvtlyelltycdsnqsphtkftelightqgqmtvlrlte
llergerlprpdrcpceiyhlmkncweteasfrptfqnlvpilqtaqekyq

Sequence, based on observed residues (ATOM records):

>d4e1za_ d.144.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
sdptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkegcgpqlrsgwqr
eieilrtlyhehivkykgccedksvqlvmeyvplgslrdylprhcvglaqlllfaqqice
gmaylhaqhyihralaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfwya
peclkeckfyyasdvwsfgvtlyelltycdsnqsphtkftelightqgqmtvlrltelle
rgerlprpdrcpceiyhlmkncweteasfrptfqnlvpilqtaqekyq

Timeline for d4e1za_:

• d4e1za_ first appeared in SCOPe 2.02
  
• d4e1za_ appears in SCOPe 2.07