Lineage for d4e20a_ (4e20 A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2222093Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2222094Protein automated matches [190417] (25 species)
    not a true protein
  7. 2223590Species Mouse (Mus musculus) [TaxId:10090] [194605] (24 PDB entries)
  8. 2223608Domain d4e20a_: 4e20 A: [194606]
    automated match to d3nz0a_
    complexed with 0my

Details for d4e20a_

PDB Entry: 4e20 (more details), 2.6 Å

PDB Description: Structure of mouse Tyk-2 complexed to a 3-aminoindazole inhibitor
PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d4e20a_:

Sequence, based on SEQRES records: (download)

>d4e20a_ d.144.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkegcgpqlrsgwqre
ieilrtlyhehivkykgccedqgeksvqlvmeyvplgslrdylprhcvglaqlllfaqqi
cegmaylhaqhyihralaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeckfyyasdvwsfgvtlyelltycdsnqsphtkftelightqgqmtvlrltel
lergerlprpdrcpceiyhlmkncweteasfrptfqnlvpilqtaqekyq

Sequence, based on observed residues (ATOM records): (download)

>d4e20a_ d.144.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkegcgpqlrsgwqre
ieilrtlyhehivkykgccedsvqlvmeyvplgslrdylprhcvglaqlllfaqqicegm
aylhaqhyihralaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfwyape
clkeckfyyasdvwsfgvtlyelltycdsnqsphtkfteligqmtvlrltellergerlp
rpdrcpceiyhlmkncweteasfrptfqnlvpilqtaqekyq

SCOPe Domain Coordinates for d4e20a_:

Click to download the PDB-style file with coordinates for d4e20a_.
(The format of our PDB-style files is described here.)

Timeline for d4e20a_: