Lineage for d4gh6b_ (4gh6 B:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2014835Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2014836Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2014926Family a.211.1.2: PDEase [48548] (7 protein domains)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 2015146Protein High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A [109942] (2 species)
  7. 2015150Species Human (Homo sapiens) [TaxId:9606] [109943] (20 PDB entries)
    Uniprot O76083 241-566
  8. 2015180Domain d4gh6b_: 4gh6 B: [194597]
    automated match to d2hd1a_
    complexed with luo, mg, zn

Details for d4gh6b_

PDB Entry: 4gh6 (more details), 2.7 Å

PDB Description: Crystal structure of the PDE9A catalytic domain in complex with inhibitor 28
PDB Compounds: (B:) High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

SCOPe Domain Sequences for d4gh6b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4gh6b_ a.211.1.2 (B:) High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4gh6b_:

Click to download the PDB-style file with coordinates for d4gh6b_.
(The format of our PDB-style files is described here.)

Timeline for d4gh6b_: