Lineage for d4ey8a_ (4ey8 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2134062Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. 2134063Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families) (S)
    many members have left-handed crossover connection between strand 8 and additional strand 9
  5. 2134064Family c.69.1.1: Acetylcholinesterase-like [53475] (6 protein domains)
    automatically mapped to Pfam PF00135
  6. 2134065Protein Acetylcholinesterase [53476] (5 species)
  7. 2134077Species Human (Homo sapiens) [TaxId:9606] [53480] (11 PDB entries)
  8. 2134090Domain d4ey8a_: 4ey8 A: [194512]
    Other proteins in same PDB: d4ey8b_
    automated match to d1maac_
    complexed with nag, so4

Details for d4ey8a_

PDB Entry: 4ey8 (more details), 2.6 Å

PDB Description: crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2
PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d4ey8a_:

Sequence, based on SEQRES records: (download)

>d4ey8a_ c.69.1.1 (A:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
rrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvd
gdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvr
vgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgar
vyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfa
rtgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat

Sequence, based on observed residues (ATOM records): (download)

>d4ey8a_ c.69.1.1 (A:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
rrratqlahlvgcpndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdflsd
tpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvpqv
sdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayvf
ehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdpn
eprdpqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat

SCOPe Domain Coordinates for d4ey8a_:

Click to download the PDB-style file with coordinates for d4ey8a_.
(The format of our PDB-style files is described here.)

Timeline for d4ey8a_: