Lineage for d2q0bb_ (2q0b B:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1221476Protein automated matches [190091] (10 species)
    not a true protein
  7. 1221597Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)
  8. 1221908Domain d2q0bb_: 2q0b B: [194450]
    automated match to d3b2tb_
    complexed with acp, so4; mutant

Details for d2q0bb_

PDB Entry: 2q0b (more details), 2.9 Å

PDB Description: crystal structure of fgf receptor 2 (fgfr2) kinase domain harboring the pathogenic e565a mutation responsible for pfeiffer syndrome
PDB Compounds: (B:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d2q0bb_:

Sequence, based on SEQRES records: (download)

>d2q0bb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatekd
lsdlvsememmkmigkhkniinllgactqdgplyvivayaskgnlreylrarrppgmeys
ydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfgl
ardinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgi
pveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlttn

Sequence, based on observed residues (ATOM records): (download)

>d2q0bb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lpedpkwefprdkltlgkplgqvvmaeavgidkdkpkeavtvavkmlkddatekdlsdlv
sememmkmigkhkniinllgactqdgplyvivayaskgnlreylrarrppeeqmtfkdlv
sctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinnidyykkttngr
lpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkeghrmdk
panctnelymmmrdcwhavpsqrptfkqlvedldriltlttn

SCOPe Domain Coordinates for d2q0bb_:

Click to download the PDB-style file with coordinates for d2q0bb_.
(The format of our PDB-style files is described here.)

Timeline for d2q0bb_: