SCOPe 2.08: Domain d2in6a_: 2in6 A:

Lineage for d2in6a_ (2in6 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d2in6a_: 2in6 A: [194370]
   automated match to d2a1ab_
   complexed with 839

Details for d2in6a_

PDB Entry: 2in6, 1.9 Å

PDB Description: Wee1 kinase complex with inhibitor PD311839

PDB Compounds: (A:) Wee1-like protein kinase

SCOPe Domain Sequences for d2in6a_:

Sequence, based on SEQRES records:

>d2in6a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mksryttefhelekigsgefgsvfkcvkrldgciyaikrskkplagsvdeqnalrevyah
avlgqhshvvryfsawaeddhmliqneycnggsladaisenyrimsyfkeaelkdlllqv
grglryihsmslvhmdikpsnifisrtsipnaaseegdeddwasnkvmfkigdlghvtri
sspqveegdsrflanevlqenythlpkadifalaltvvcaagaeplprngdqwheirqgr
lpripqvlsqeftellkvmihpdperrpsamalvkhsvl

Sequence, based on observed residues (ATOM records):

>d2in6a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mksryttefhelekigsgefgsvfkcvkrldgciyaikrskkpsvdeqnalrevyahavl
gqhshvvryfsawaeddhmliqneycnggsladaisenyrimsyfkeaelkdlllqvgrg
lryihsmslvhmdikpsnifiskvmfkigdlghvtrisspqveegdsrflanevlqenyt
hlpkadifalaltvvcaagaeplprngdqwheirqgrlpripqvlsqeftellkvmihpd
perrpsamalvkhsvl

Timeline for d2in6a_:

• d2in6a_ first appeared in SCOPe 2.02
  
• d2in6a_ appears in SCOPe 2.07