Lineage for d3v66a_ (3v66 A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2337561Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 2337562Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 2337697Family a.128.1.2: Squalene synthase [48580] (2 proteins)
    automatically mapped to Pfam PF00494
  6. 2337703Protein automated matches [191305] (1 species)
    not a true protein
  7. 2337704Species Human (Homo sapiens) [TaxId:9606] [190011] (24 PDB entries)
  8. 2337715Domain d3v66a_: 3v66 A: [194203]
    automated match to d1ezfb_
    complexed with d3a, po4

Details for d3v66a_

PDB Entry: 3v66 (more details), 1.8 Å

PDB Description: human squalene synthase in complex with 2-(1-{2-[(4r,6s)-8-chloro-6-(2,3-dimethoxyphenyl)-4h,6h-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetic acid
PDB Compounds: (A:) Squalene synthase

SCOPe Domain Sequences for d3v66a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3v66a_ a.128.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3v66a_:

Click to download the PDB-style file with coordinates for d3v66a_.
(The format of our PDB-style files is described here.)

Timeline for d3v66a_: