SCOPe 2.05: Domain d4dc0b_: 4dc0 B:

Lineage for d4dc0b_ (4dc0 B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein automated matches [190085] (47 species)
   not a true protein

7. Species Streptomyces coelicolor [TaxId:1902] [189970] (5 PDB entries)

8. Domain d4dc0b_: 4dc0 B: [194150]
   automated match to d2rhcb_
   complexed with ndp

Details for d4dc0b_

PDB Entry: 4dc0, 2.81 Å

PDB Description: Crystal Structure of F189W Actinorhodin Polyketide Ketoreductase with NADPH

PDB Compounds: (B:) ketoacyl reductase

SCOPe Domain Sequences for d4dc0b_:

Sequence; same for both SEQRES and ATOM records:

>d4dc0b_ c.2.1.2 (B:) automated matches {Streptomyces coelicolor [TaxId: 1902]}
matqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelreagveadgr
tcdvrsvpeiealvaavverygpvdvlvnnagrpgggataeladelwldvvetnltgvfr
vtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalglelartgi
tvnavcpgwvetpmaasvrehysdiwevsteeafdritarvpigryvqpsevaemvayli
gpgaaavtaqalnvcgglgny

Timeline for d4dc0b_:

• d4dc0b_ first appeared in SCOPe 2.02
  
• d4dc0b_ appears in SCOPe 2.04
  
• d4dc0b_ appears in SCOPe 2.06
  
• d4dc0b_ appears in the current release, SCOPe 2.08