SCOPe 2.02: Domain d3nlba_: 3nlb A:

Lineage for d3nlba_ (3nlb A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Homo sapiens [TaxId:9606] [192729] (55 PDB entries)

8. Domain d3nlba_: 3nlb A: [193706]
   automated match to d2x8da_
   complexed with 5be

Details for d3nlba_

PDB Entry: 3nlb, 1.9 Å

PDB Description: Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death

PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d3nlba_:

Sequence, based on SEQRES records:

>d3nlba_ d.144.1.7 (A:) automated matches {Homo sapiens [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmlnhe
nvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgig
ithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefh
aepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhki
lvenpsaritipdikkdrwynkplkk

Sequence, based on observed residues (ATOM records):

>d3nlba_ d.144.1.7 (A:) automated matches {Homo sapiens [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkrenikkeicinkmlnhenvvkf
yghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrd
ikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvd
vwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenp
saritipdikkdrwynkplkk

Timeline for d3nlba_:

• d3nlba_ is new in SCOPe 2.02-stable
  
• d3nlba_ appears in SCOPe 2.03
  
• d3nlba_ appears in the current release, SCOPe 2.08