SCOPe 2.08: Domain d4fa8g1: 4fa8 G:4-148

Lineage for d4fa8g1 (4fa8 G:4-148)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)

6. Protein automated matches [190501] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187448] (21 PDB entries)

8. Domain d4fa8g1: 4fa8 G:4-148 [193551]
   Other proteins in same PDB: d4fa8e2, d4fa8f2, d4fa8g2
   automated match to d1hmca_
   complexed with nag

Details for d4fa8g1

PDB Entry: 4fa8, 2.2 Å

PDB Description: multi-pronged modulation of cytokine signaling

PDB Compounds: (G:) macrophage colony-stimulating factor 1

SCOPe Domain Sequences for d4fa8g1:

Sequence; same for both SEQRES and ATOM records:

>d4fa8g1 a.26.1.2 (G:4-148) automated matches {Human (Homo sapiens) [TaxId: 9606]}
seycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdimed
tmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvfne
tknlldkdwnifskncnnsfaecss

Timeline for d4fa8g1:

• d4fa8g1 first appeared in SCOPe 2.02, called d4fa8g_
  
• d4fa8g1 appears in SCOPe 2.07