Lineage for d4hlca_ (4hlc A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2113903Family c.37.1.0: automated matches [191323] (1 protein)
    not a true family
  6. 2113904Protein automated matches [190123] (130 species)
    not a true protein
  7. 2114700Species Staphylococcus aureus [TaxId:282458] [193407] (7 PDB entries)
  8. 2114701Domain d4hlca_: 4hlc A: [193408]
    automated match to d2ccja_
    complexed with t05

Details for d4hlca_

PDB Entry: 4hlc (more details), 1.55 Å

PDB Description: Sulfonylpiperidines as Novel, Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase (TMK): Compound 5
PDB Compounds: (A:) thymidylate kinase

SCOPe Domain Sequences for d4hlca_:

Sequence, based on SEQRES records: (download)

>d4hlca_ c.37.1.0 (A:) automated matches {Staphylococcus aureus [TaxId: 282458]}
safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdirt
eamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefain
glypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfksv
nadqplenvvedtyqtiikyle

Sequence, based on observed residues (ATOM records): (download)

>d4hlca_ c.37.1.0 (A:) automated matches {Staphylococcus aureus [TaxId: 282458]}
safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdirt
eamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefain
glypdltiylnvsaevgreriikldqedlkfhekviegyqeiihnesqrfksvnadqple
nvvedtyqtiikyle

SCOPe Domain Coordinates for d4hlca_:

Click to download the PDB-style file with coordinates for d4hlca_.
(The format of our PDB-style files is described here.)

Timeline for d4hlca_: