SCOPe 2.02: Domain d4eh4a_: 4eh4 A:

Lineage for d4eh4a_ (4eh4 A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)

8. Domain d4eh4a_: 4eh4 A: [193347]
   automated match to d1wbsa_
   complexed with 0ol, irg

Details for d4eh4a_

PDB Entry: 4eh4, 2.5 Å

PDB Description: Human p38 MAP kinase in complex with NP-F3 and RL87

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d4eh4a_:

Sequence, based on SEQRES records:

>d4eh4a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld

Sequence, based on observed residues (ATOM records):

>d4eh4a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsygsvcaafdtktglrvavkklsrpfqsiiha
krtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkkltddhv
qfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglavatrwyrapeimlnw
mhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarn
yiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpdde
pvadpydqsfesrdllidewksltydevisfvpppld

Timeline for d4eh4a_:

• d4eh4a_ is new in SCOPe 2.02-stable
  
• d4eh4a_ appears in SCOPe 2.03
  
• d4eh4a_ appears in the current release, SCOPe 2.08