SCOPe 2.08: Domain d4iwhb_: 4iwh B:

Lineage for d4iwhb_ (4iwh B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
   the active site is between the two identical subunits

6. Protein automated matches [190072] (22 species)
   not a true protein

7. Species Burkholderia thailandensis [TaxId:271848] [193254] (1 PDB entry)

8. Domain d4iwhb_: 4iwh B: [193255]
   Other proteins in same PDB: d4iwha2
   automated match to d1a05a_
   complexed with mg

Details for d4iwhb_

PDB Entry: 4iwh, 1.75 Å

PDB Description: Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei

PDB Compounds: (B:) 3-isopropylmalate dehydrogenase

SCOPe Domain Sequences for d4iwhb_:

Sequence; same for both SEQRES and ATOM records:

>d4iwhb_ c.77.1.1 (B:) automated matches {Burkholderia thailandensis [TaxId: 271848]}
mkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpdatlalakea
dailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdasplkpelva
gldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriahvafqaaqk
rakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakapkqfdvivt
gnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgianplatilsa
amllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavvaal

Timeline for d4iwhb_:

• d4iwhb_ first appeared in SCOPe 2.02
  
• d4iwhb_ appears in SCOPe 2.07