SCOPe 2.07: Domain d4jbyb_: 4jby B:

Lineage for d4jbyb_ (4jby B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidine kinase [52552] (4 species)
   contains insert all-alpha subdomain, res. 251-322

7. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (33 PDB entries)
   Uniprot P03176 46-375

8. Domain d4jbyb_: 4jby B: [193222]
   automated match to d1p7cb_
   protein/DNA complex; complexed with edo, fsk, so4

Details for d4jbyb_

PDB Entry: 4jby, 2 Å

PDB Description: Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with F-SK78

PDB Compounds: (B:) Thymidine kinase

SCOPe Domain Sequences for d4jbyb_:

Sequence, based on SEQRES records:

>d4jbyb_ c.37.1.1 (B:) Thymidine kinase {Herpes simplex virus type 1, different strains [TaxId: 10298]}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremge

Sequence, based on observed residues (ATOM records):

>d4jbyb_ c.37.1.1 (B:) Thymidine kinase {Herpes simplex virus type 1, different strains [TaxId: 10298]}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeapppaltlifdrhpiaall
cypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldla
mlaairrvygllantvrylqcggswredwgqlsgpqsnagprphigdtlftlfrapella
pngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsip
ticdlartfaremge

Timeline for d4jbyb_:

• d4jbyb_ first appeared in SCOPe 2.02
  
• d4jbyb_ appears in SCOPe 2.06
  
• d4jbyb_ appears in the current release, SCOPe 2.08