Lineage for d4drhe1 (4drh E:2025-2112)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1987359Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  4. 1987732Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family) (S)
    automatically mapped to Pfam PF08771
  5. 1987733Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 protein domains)
  6. 1987744Protein automated matches [193175] (1 species)
    not a true protein
  7. 1987745Species Human (Homo sapiens) [TaxId:9606] [193176] (4 PDB entries)
  8. 1987749Domain d4drhe1: 4drh E:2025-2112 [193177]
    Other proteins in same PDB: d4drha_, d4drhb2, d4drhd_, d4drhe2
    automated match to d1aueb_
    complexed with rap, so4

Details for d4drhe1

PDB Entry: 4drh (more details), 2.3 Å

PDB Description: Co-crystal structure of the PPIase domain of FKBP51, Rapamycin and the FRB fragment of mTOR at low pH
PDB Compounds: (E:) Serine/threonine-protein kinase mTOR

SCOPe Domain Sequences for d4drhe1:

Sequence, based on SEQRES records: (download)

>d4drhe1 a.24.7.1 (E:2025-2112) automated matches {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4drhe1 a.24.7.1 (E:2025-2112) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4drhe1:

Click to download the PDB-style file with coordinates for d4drhe1.
(The format of our PDB-style files is described here.)

Timeline for d4drhe1: