SCOP 1.65: Domain d1fm6x_: 1fm6 X:

Lineage for d1fm6x_ (1fm6 X:)

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (25 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (10 PDB entries)

8. Domain d1fm6x_: 1fm6 X: [19317]
   Other proteins in same PDB: d1fm6a_, d1fm6u_
   complexed with brl, rea

Details for d1fm6x_

PDB Entry: 1fm6, 2.1 Å

PDB Description: the 2.1 angstrom resolution crystal structure of the heterodimer of the human rxralpha and ppargamma ligand binding domains respectively bound with 9-cis retinoic acid and rosiglitazone and co-activator peptides.

SCOP Domain Sequences for d1fm6x_:

Sequence; same for both SEQRES and ATOM records:

>d1fm6x_ a.123.1.1 (X:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens)}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfk
hitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhei
iytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdla
ifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqi
vtehvqllqvikktetdmslhpllqeiykdly

Timeline for d1fm6x_:

• d1fm6x_ first appeared (with stable ids) in SCOP 1.55
  
• d1fm6x_ appears in SCOP 1.63
  
• d1fm6x_ appears in SCOP 1.67
  
• d1fm6x_ appears in the current release, SCOPe 2.08